不用再找了!2025 IMS 会议中国入选研究一篇汇总
2025-09-02 来源:医脉通
关键词: 2025 IM


医脉通编辑整理,未经授权请勿转载。


第22届国际骨髓瘤学会(IMS)年会将于2025年9月17-20日在加拿大多伦多举行。国际骨髓瘤学会致力于汇聚从事骨髓瘤研究的临床和试验研究者,在全球范围内推动多发性骨髓瘤领域的教育、临床研究(包括诊断和治疗)以及会议的开展。国际骨髓瘤学会年会作为骨髓瘤领域的权威年度会议,聚焦基础研究、临床前研究及临床研究三大方向。今年,中国专家共有5篇研究入选Oral Presentations,83篇研究入选Poster Presentations,下面紧随小编步伐,一睹中国专家们的风采!


Oral Presentations


摘要号
标题
第一作者
及单位
OA-08
Three-Year Follow-Up of FUMANBA-1: a Phase 1b/ 2 Study of Fully Human Anti-BCMA CAR-T Equecabtagene Autoleucel in Patients with Relapsed/Refractory Multiple Myeloma
李春蕊,华中科技大学同济医学院附属同济医院
OA-16
BCMACAR T-Cell Therapy in Newly Diagnosed Primary Plasma Cell Leukemia Ineligible for Transplantation: An Open Label, Single-arm, Phase 2 Study (CAREMM-002)
Wenqiang Yan,中国医学科学院血液病医院(中国医学科学院血液学研究所)
OA-36
Bone Marrow-Homing and Chimeric Antigen Receptor-Engineered Lipid Nanoparticles Enable Sequential miRNA Delivery for Precision Therapy of Multiple Myeloma
Huaqing Jing,中国医学科学院血液病医院(中国医学科学院血液学研究所)
OA-39
Targeting PHF19 Inhibits Myeloma Progression and Increases IMiDs Sensitivity by Epigenetically Regulating MYC and IRF4 Pathway
Xiyue Sun,中国医学科学院血液病医院(中国医学科学院血液学研究所)
OA-40
A Novel Dual Proteasome and HDAC6 Inhibitor I3MV-8b Potentiates Anti-CD38 Monoclonal Antibody Efficacy in Multiple Myeloma
Xiaoyu Zhang,中国医学科学院血液病医院(中国医学科学院血液学研究所)


Poster Presentations


摘要号
标题
第一作者
及单位
PA-021
First-in-Human Study of GPRC5D-Targeted CAR T-cell Therapy CT071 with an Accelerated Manufacturing Process for the Treatment of Relapsed/Refractory Multiple Myeloma
Lina Jin,上海长征医院
PA-029
Long Term Follow-Up of Zevor-Cel in Patients with Relapsed/Refractory Multiple Myeloma
傅琤琤,苏州大学附属第一医院
PA-055
CAR-TscmCells as anEffective ImmuneTreatment to Multiple Myeloma Patients
Zhaoyun Liu,天津医科大学总医院
PA-056
CAC-MM-001: Anti-BCMACAR-T Therapy Followed by Autologous Stem Cell Transplantation and Second CAR-T (CART-ASCT-CART2) in Newly Diagnosed Multiple Myeloma Patients with P53 Gene Abnormalities
Yuntong Liu,中国医学科学院血液病医院(中国医学科学院血液学研究所)
PA-065
Real-World Outcomes of Equecabtagene Autoleucel, the First Fully Human BCMA-Targeted CAR-T Therapy, in 150 Patients with Multiple Myeloma (MM): A Multicenter Experience from China
Jin Lu,北京大学人民医院
PA-066
Kinetic Characteristics of T Cells in CAR-T Therapy for Multiple Myeloma: A Real-World Analysis
蔡真,浙江大学医学院附属第一医院
PA-095
Efficacy and Safety of CAR-T Therapy in CNS-MM
Weiwei Tian,山西白求恩医院
PA-105
CART–ASCT–CART2 Sandwich Regimen as Frontline Therapy: A Phase II Trial in Patients with Primary Plasma Cell Leukemia
Jingyu Xu,中国医学科学院血液病医院(中国医学科学院血液学研究所)
PA-106
BCMACAR T-Cell Therapy in Newly Diagnosed Transplant-ineligible Multiple Myeloma: An Open Label, Single-arm, Phase 2 Study (CAREMM-001)
Wenqiang Yan,中国医学科学院血液病医院(中国医学科学院血液学研究所)
PA-107
Impact of Frailty Tools on Outcomes in Myeloma: MRP and Simplified Index Predict Survival but Differ in Infection Risk Stratification
Shaoli Zhang,山西白求恩医院
PA-108
A Comparison of Chemo-free Strategy with Plerixafor Plus G-CSF Versus High-Dose Cyclophosphamide Plus G-CSF as First-line PBSC Mobilization in Multiple Myeloma Patients: A Chinese Explorative Study
Xiaoyan Han,浙江大学医学院附属第一医院
PA-110
Denosumab-Related Osteonecrosis of the Jaw in Patients with Multiple Myeloma: AChinese Single Center Retrospective Cohort Study
Bin Chu,北京积水潭医院
PA-134
Factors Influencing the Outcome of Salvage Second Autologous Stem Cell Transplant in Relapsed Multiple Myeloma
Yanjuan Li,中山大学附属第一医院
PA-137
Predicting Early Mortality Risk in Newly Diagnosed
 Multiple Myeloma Patients
Chia-Jen Liu,台北荣民总医院
PA-157
Incidence and Risk Factors of Thromboembolic Events in Chinese Patients with Multiple Myeloma: A Single-Center Retrospective Cohort Study
Yunge Xu,北京协和医院
PA-160
Dialysis-Dependence is Associated with Poor Prognosis in Multiple Myeloma: a Multicenter Retrospective Cohort Study
Chenyun Wang,浙江大学医学院附属第一医院
PA-164
Serum Cholesterol Levels Demonstrate Dynamic Changes Following Autologous Hematopoietic StemCell Transplantation in Patients with Multiple Myeloma
Yuan Chen,北京积水潭医院
PA-173
Quantitative CD38 Expression and Clinical Response to Anti-CD38 Therapy in Multiple Myeloma: A Retrospective Cohort Analysis
Jianlin Hu,华中科技大学同济医学院附属同济医院
PA-177
Circulating Plasma Cells as an Independent Prognostic Marker in Newly Diagnosed Multiple Myeloma: Clinical Correlation and Immunophenotypic Insights
Yating Li,中国医学科学院血液病医院(中国医学科学院血液学研究所)
PA-179
Verification and Optimization of VTE Risk Stratification System for Multiple Myeloma in China Based on Review Cohort
Yuexiao Liu,首都医科大学附属复兴医院
PA-180
Revealing Clonal Evolution and Assessing Immune Reconstitution in Multiple Myeloma Using Next Generation Sequencing-Based Minimal Residual Disease (NGS-MRD) Analysis
Yuntong Liu,中国医学科学院血液病医院(中国医学科学院血液学研究所)
PA-198
Identification of a CAR–Derived Clone by NGS Based MRD After Fully Human BCMA CAR T-Cell Therapy in Multiple Myeloma
Wenqiang Yan,中国医学科学院血液病医院(中国医学科学院血液学研究所)
PA-200
Performance and Additional Benefits of Matrix Assisted Laser Desorption/Ionization-Time-of Flight Mass Spectrometry in M-Protein Detection in Plasma Cell Disorders
Mengmeng Dong,浙江大学医学院附属第一医院
PA-201
Delayed and Sustained Minimal Residual Disease Response Predicts Favorable Outcomes in Newly Diagnosed Multiple Myeloma
Jieqiong Zhou,中国医学科学院血液病医院(中国医学科学院血液学研究所)
PA-202
Dynamic Changes in Cytogenetic Abnormalities Detected by Serial FISH Predict MRD Status and Outcomes in Multiple Myeloma
Jieqiong Zhou,中国医学科学院血液病医院(中国医学科学院血液学研究所)
PA-217
Potential Roles of YBX1-MIF Axis in Promoting Bone Marrow Inflammation and Multiple Myeloma Progression
Mengping Chen,上海交通大学医学院附属仁济医院
PA-218
Bortezomib, Lenalidomide, and Dexamethasone Reverses the Inferior Prognostic Effect of KRAS Mutation in Patients with Newly-Diagnosed Multiple Myeloma
Lili Cheng,北京协和医院
PA-221
Type I Interferon Pathway Activation Disrupts Monocyte Maturation and Enhances Immune Evasion in Multiple Myeloma
Jian Cui,中国医学科学院血液病医院(中国医学科学院血液学研究所)
PA-225
Development of a Cytogenetic Double-Hit Model for Survival Prediction in Multiple Myeloma
Chenxing Du,中国医学科学院血液病医院(中国医学科学院血液学研究所)
PA-226
MYC Copy Number Variation Detected by FISH Indicates a Similarly Poor Prognosis to MYC Rearrangement in Newly Diagnosed Multiple Myeloma
Chenxing Du,中国医学科学院血液病医院(中国医学科学院血液学研究所)
PA-235
Imbalance of Glycine Metabolism Contributes to Osteolysis in Multiple Myeloma
Cong Hu,中南大学肿瘤研究所
PA-243
Role and Mechanism of Multiple Myeloma Cells in Regulating Macrophage Polarization and the Antitumor Effect via ENO1
Zhaoyun Liu,天津医科大学总医院
PA-244
Targeting PIM-2 and PARP1 Induces MICA Expression on Multiple Myeloma Cells to Activate NK Cells Through NKG2D Binding
Zhaoyun Liu,天津医科大学总医院
PA-245
Targeting Lactate Metabolism in Multiple Myeloma to Enhance CAR-T Cells Antitumor Function
Zhaoyun Liu,天津医科大学总医院
PA-246
LILRB4 Drives Myeloid Immunosuppressive Microenvironment in Multiple Myeloma and Facilitates the Inferior Outcome of Patients
Lanting Liu,中国医学科学院血液病医院(中国医学科学院血液学研究所)
PA-272
Dual Roles of IRE1α Inhibition in Reversing Mitochondrial ROS-Induced CD8+ T Cell Senescence and Exerting Direct Anti-Tumor Effects in Multiple Myeloma
Yike Wan,上海交通大学医学院附属仁济医院
PA-273
Insights into Ubiquitination-Associated Genes in Multiple Myeloma: A Multi-Omics Mendelian Randomization Study
Jinuo Wang,浙江大学医学院附属第一医院
PA-276
Macrophages Promote Aberrant DNA Repair in

 Multiple Myeloma Via the CXCL5/CXCR2 Axis
Mengmeng Dong,浙江大学医学院附属第一医院
PA-277
Crosstalk Between m6A and H3K27ac via the YTHDC1-EP300 Feedback Loop Promotes Myelomagenesis
Yifan Hou,浙江大学医学院附属第一医院
PA-278
NAMPT in Myeloma-Associated Macrophages Drives Drug Resistance through Mitochondrial Metabolic Reprogramming and Immune Evasion via the SIRT1/STAT3/SPP1 Axis
Shunnan Yao,浙江大学医学院附属第一医院
PA-279
NEDD4-1-Mediated Ubiquitination of CCR7 Reprograms Macrophage Function and Enhances theraputic Sensitivity in Multiple Myeloma
Xi Huang,浙江大学医学院附属第一医院
PA-280
The m5C-Binding Protein YB-1 Modulates Proteasome Inhibitors Resistance in Multiple Myeloma Via Epigenetic Modification
Qiqi Shen,浙江大学医学院附属第一医院
PA-281
LILRB4 Drives Daratumumab Resistance in Multiple Myeloma via STAT3/PIM1 Activation and Lipid Metabolic Reprogramming of the Immune Microenvironment
Xiaoyu Zhang,中国医学科学院血液病医院(中国医学科学院血液学研究所)
PA-289
Enhanced Expression of TAGLN2 Predicts Negative
 Prognosis in Multiple Myeloma
Mengping Chen,上海交通大学医学院附属仁济医院
PA-301
Enhancing Immunotherapy through Metabolic
 Modulation in Humanized Multiple Myeloma Mice
Zhaoyun Liu,天津医科大学总医院
PA-302
Role and Mechanism of Pim-2 Kinase Inhibitors induced Immunogenic Cell Death in Multiple Myeloma
Zhaoyun Liu,天津医科大学总医院
PA-303
STAT3Inhibitors Inducing DNA DamageinMultiple Myeloma Cells and Enhancing the Anti-Tumor Effects of NK Cells
Zhaoyun Liu,天津医科大学总医院
PA-323
LILRB4 Protects Multiple Myeloma Cells from
 Ferroptosis to Promote MM Progression
Yijie Wang,中国医学科学院血液病医院(中国医学科学院血液学研究所)
PA-324
AKR1B1/NAT10 Mediate IL4I1 ac4C Modification to Regulate Tryptophan Metabolism and Promote Multiple Myeloma Proliferation
Rongfang Wei,中山大学附属第八医院
PA-325
RNF5-DNAJA1 Axis Dictates Selinexor Sensitivity of Multiple Myeloma
Yinyin Xu,重庆医科大学
PA-327
Carfilzomib, Pomalidomide, Dexamethasone ± Daratumumab Delivers Survival Benefit Regardless of Cytogenetic Risk in Early Relapsed Myeloma Patients-A Multi-Center, Prospective Real World Study in China
Fujing Zhang,北京协和医院
PA-328
Inhibition of DNA Damage Response Factor DNA PKcs-Mediated H2AX Phosphorylation Enhances Selinexor-Induced Anti-Multiple Myeloma Effects
Jinna Zhang,浙江大学医学院附属第一医院
PA-329
A Multi-Step Virtual Screening Framework Identifies Novel GPRC5D Inhibitors for Multiple Myeloma Therapy
Xi Chen,浙江大学医学院附属第一医院
PA-330
Prognostic Determinants of Overall Survival in POEMS Syndrome: A 7-Year Single-Center Retrospective Analysis
Yuhan Bao,华中科技大学同济医学院附属同济医院
PA-332
Clinical Study on the Efficacy and Safety of Aponermin Combined with Dexamethasone Based Regimen in Multidrug-Resistant Multiple Myeloma
Meilan Chen,中山大学附属第一医院
PA-352
The Study of Serum VEGF Expression in Different Types of Plasma Cell Diseases
Xiujin Li,中山大学附属第一医院
PA-353
Analysis of Clinical Characteristics and Prognostic Factors in Patients with Primary Plasma Cell Leukemia
Xiujin Li,中山大学附属第一医院
PA-354
Profound Decrease of dFLC After One Cycle Predicts Superior Outcome in Patients with AL Amyloidosis Treated with Daratumumab and Bortezomib-Based Regimens
Yang Liu,北京大学人民医院
PA-370
Efficacy and Safety of Daratumumab-Based Regimens in Light Chain Amyloidosis: A Retrospective Single-Center Study
Xinran Wang,华中科技大学同济医学院附属同济医院
PA-371
Integrative Clinical, Transcriptomic, and Immunohistochemical Characterization of Light Chain Amyloidosis in Bone Marrow and Cardiac Tissue
Chao-Hung Wei,台湾大学医学院附设医院
PA-377
Efficacy and Safety of Daratumumab, Lenalidomide, and Dexamethasone in Transplant Ineligible Newly Diagnosed Multiple Myeloma Patients: A Single-Center Real-World Study in China
Li-Juan Fang,北京积水潭医院
PA-378
Steady-State Hematopoietic Cell Mobilization for Newly Diagnosed Multiple Myeloma Patients Receiving Daratumumab-Based Induction Therapy Versus IMiD-Based Induction Therapy: A Real- World Experience
鲍立,北京积水潭医院
PA-383
HSPA9 Contributes to Tumor Progression and Ferroptosis Resistance by Enhancing Usp14 Driven xCT Deubiquitination in Multiple Myeloma
Na Shen,江苏省人民医院
PA-384
Impact of CD34+ Cell Infusion Dose on Immune reconstitution and Survival in Multiple Myeloma after Autologous Stem Cell Transplantation
Lijuan Chen,江苏省人民医院
PA-400
D-VRd-based Dynamic Frailty-Tailored Therapy (DynaFiT-v2) in Elderly Patients with Newly Diagnosed Multiple Myeloma: a Prospective Study
Yingjie Zhang,吉林大学第一医院
PA-452
Interim Analysis of DARAVRD in the Treatment of TE-NDMM Patients with Standard Risk Who Refused to Accept ASCT as First Line in China
傅琤琤,苏州大学附属第一医院
PA-454
Daratumumab, Lenalidomide, Bortezomib, and Dexamethasone for Newly Diagnosed Multiple Myeloma: Outcome and Safety Profile from a Multi-Center Real-World Experience
Yue Wu,首都医科大学附属复兴医院
PA-455
Dara-VCd in Newly Diagnosed Multiple Myeloma with Severe Renal Impairment: A Prospective Multicenter Single-Arm Study
Yang Yang,浙江大学医学院附属第一医院
PA-457
Early Identification of Patients with Multiple Myeloma Progressing within a Short-Term following Tandem Transplantation
Tongyong Yu,中山大学附属第一医院
PA-458
Autologous Peripheral Blood Hematopoietic Stem Cell Transplantation on the Treatment of Multiple Myeloma: ASingle-Center Clinical Analysis on PFS
Hailong Yuan,新疆医科大学第一附属医院
PA-459
Efficacy and Safety of Ixazomib-Based Maintenance Therapy after Autologous Hematopoietic Stem Cell Transplantation in Multiple Myeloma Patients: A Retrospective Analysis
Hailong Yuan,新疆医科大学第一附属医院
PA-460
Efficacy and Safety of Biweekly/Weekly Ixazomib Dexamethasone Maintenance Therapy in Chinese Patients with Newly Diagnosed Multiple Myeloma: A Multi-Center Study
Xiaoyan Han,浙江大学医学院附属第一医院
PA-461
Selinexor Combined Bortezomib, Lenalidomide, andDexamethasonefor NewlyDiagnosedMultiple Myeloma with High-Risk Cytogenetics Abnormalities: A Single-Arm, Multi-Center, Observational Clinical Study
Junjing Yin,青岛市立医院
PA-488
Efficacy and Safety of a China-Developed BCMA Targeted CAR-T Therapy (Eque-cel) in Plasma Cell Leukemia: Real-World Multicenter Experience
Dou Xuelin,北京大学人民医院
PA-511
Exploration of Efficacy for Frailty-Adjusted Dose Reduced Pcd Regimen in Relapsed/Refractory Multiple Myeloma
Weiwei Tian,山西白求恩医院
PA-513
Clinical Features and Management of GPRC5D related AE in Chinese Relapsed/Refractory Multiple Myeloma Patients Treated with Talquetamab: MonumenTAL-1 China Cohort Experience
安刚,中国医学科学院血液病医院(中国医学科学院血液学研究所)
PA-514
Real-World Treatment Patterns, Effectiveness, and Safety of Daratumumab-based Regimens in Chinese Patients with Multiple Myeloma: Final Analysis of the MMY4032 Study
王鲁群,山东大学齐鲁医院
PA-517
BCMA CAR-T Therapy with Radiotherapy Bridging and Maintenance Achieves Unprecedented Complete Response in Extramedullary Myeloma
Lily Zhou,上海曜影医院
PA-518
Case Report: BCMA-targeting CAR T-cell Therapy Induces Complete and Durable Remission in Relapsed Extramedullary Plasmablastic Multiple Myeloma
Lily Zhou,上海曜影医院
PA-520
Efficacy and Safety of Low-frequency Daratumumab in Systemic Light-chain Amyloidosis
Donghua He,浙江大学医学院附属第一医院
PA-522
Glycosylation Single-Cell Transcriptomic Profiling Decodes Driver Mechanism and Genetic Characteristics of Circulating Plasma Cells in Multiple Myeloma
屈晓燕,江苏省人民医院
PA-531
Single-Cell Sequencing Reveals Transcriptional and Metabolic Divergence of Bone-Involved Multiple Myeloma
Dian Tong,江苏省人民医院
PA-533
Nutritional Status Indices on the Prognosis of Patients with Relapsed and Refractory Multiple Myeloma Treated with CAR-T Cell Immunotherapy
Peng Xu,徐州医科大学附属医院


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本文仅筛选了全部作者均来自中国的研究


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