ESC 2019前瞻:5大重磅指南、一大波热点研究,正在路上!
2019-07-25 来源:医脉通

医脉通编译整理,未经授权请勿转载。


8月31日至9月4日,2019欧洲心脏病学会年会(ESC 2019)将在法国巴黎盛大召开。作为全世界规模最大、最具影响力的心血管学术会议,ESC 2019将对整个心脏病学的各个领域进行全面的更新。本次大会ESC将与世界心脏联盟(WHF)共同组织,与世界心脏病学大会(WCC)联合举办,聚集全球心血管健康,突出世界各地在心血管疾病流行病学、临床表现、预防策略、诊断方式以及管理方面的差异。


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每年最受瞩目的当然是指南和重磅研究。ESC 2019拟发布5部指南,还有26项最新临床研究结果(Hot Line),必将会对全球心血管疾病的临床实践产生重要影响。同样值得期待的是,本次大会上,ESC将与中华医学会心血管病学分会(Chinese Society of Cardiology, CSC)和长城国际心脏病学大会(Great Wall International Congress of Cardiology, GWICC)协作,开设两个联合专场。


五部临床实践指南


9月1日至3日,在ESC 2019的主会场将发布5部临床指南,分别是慢性冠状动脉综合征指南、血脂异常指南、糖尿病/糖尿病前期和心血管疾病指南、急性肺栓塞指南以及室上性心动过速指南。


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6个热门研究专场,26项最新临床研究


9月1日至3日,在主会场,将设置6个热门研究专场(Hot Line Session),公布26项最新临床研究结果。这些都是最近完成的、尚未发表的重大研究结果。


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Hot Line Session 1


时间:Sun 01 Sep,14:30 - 15:40

地点:Paris - Main Auditorium


THEMIS - Main Results of the Effect of Ticagrelor on Health Outcomes in Diabetes Mellitus Patients Intervention Study

THEMIS研究主要结果,评估了在冠心病合并2型糖尿病患者中,替格瑞洛对健康结局的影响(替格瑞洛+阿司匹林vs阿司匹林单药)


THEMIS-PCI - Ticagrelor in Patients with Diabetes and Stable Coronary Artery Disease with a History of Prior Percutaneous Coronary Intervention

替格瑞洛在糖尿病合并稳定性冠状动脉疾病且有PCI治疗史的患者中的应用


PARAGON-HF - Angiotensin Receptor Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction

在射血分数保留的心衰(HFpEF)治疗中,血管紧张素受体脑啡肽酶抑制剂(ARNI)沙库巴曲/缬沙坦的作用评价


COMPLETE Revascularization with Multivessel Percutaneous Coronary Intervention in ST-segment Elevation Myocardial Infarction

评估STEMI患者的多支血管PCI(FFR引导的完全血运重建)


Hot Line Session 2


时间:Sun 01 Sep,16:40 - 17:52

地点:Paris - Main Auditorium


NZOTACS - The New Zealand Oxygen Therapy in Acute Coronary Syndromes trial

新西兰氧疗法在急性冠脉综合征中的应用


CONDI-2/ERIC-PPCI - Effect of remote ischemic conditioning on clinical outcomes in patients with ST- segment elevation myocardial infarction undergoing primary percutaneous coronary intervention

在接受PCI治疗的STEMI患者中,远隔缺血适应(Remote Ischemic Conditioning, RIC)对临床结局的影响


ISAR-REACT 5 - Ticagrelor Versus Prasugrel in Patients With Acute Coronary Syndrome

替格瑞洛和普拉格雷用于急性冠脉综合征患者的比较


HiSTORIC - High-Sensitivity cardiac Troponin On presentation to Rule out myocardial InfarCtion: A stepped-wedge cluster randomised controlled trial

高敏肌钙蛋白在排除心肌梗死诊断中的应用:一项阶梯楔形群随机对照试验


Hot Line Session 3


时间:Mon 02 Sep,11:00 - 12:30

地点:Paris - Main Auditorium


Combined effect of lower LDL-C and lower SBP on the lifetime risk of cardiovascular disease

较低的LDL-C和收缩压对心血管疾病终生风险的综合影响


AFIRE - Rivaroxaban monotherapy versus dual therapy in patients with atrial fibrillation and stable coronary artery disease

房颤合并稳定性冠状动脉疾病患者中,利伐沙班单药与双联治疗的比较


GALACTIC - Goal-directed AfterLoad Reduction in Acute Congestive Cardiac Decompensation: a randomized controlled trial

目标导向的后负荷降低对急性充血性心脏失代偿的影响:一项随机对照试验


Salt substitution and community-wide reductions in blood pressure and hypertension incidence

盐替代和社区范围内的血压降低以及高血压发病率


HOPE 4 - Impact on cardiovascular risk of a community-based multi-faceted intervention in individuals with hypertension in 2 middle income countries: The Heart Outcomes Prevention and Evaluation 4 study

在两个中等收入国家中评估基于社区的多方面干预对高血压患者心血管风险的影响


Hot Line Session 4


时间:Mon 02 Sep,16:40 - 17:52

地点:Paris - Main Auditorium


BB-meta-HF - Beta-blockers are effective in high-risk heart failure patients with reduced ejection fraction and moderately-severe renal dysfunction

对于高危射血分数降低的心衰(HFrEF)合并中重度肾功能不全的患者,β受体阻滞剂有效


SYNTAXES - Ten-Year Survival after Coronary Artery Bypass Grafting versus Percutaneous Coronary Intervention: The SYNTAX Extended Survival study

冠状动脉旁路移植术与经皮冠状动脉介入术后的10年生存率:SYNTAX扩展生存研究


MITRA-FR - 2 years follow-Up of the MITRA-FR study a randomized controlled trial evaluating the effectiveness of percutaneous mitral valve repair in secondary mitral regurgitation

评估经皮二尖瓣修复在继发性二尖瓣关闭不全中的有效性:MITRA-FR随机对照试验的2年随访结果


DANAMI-2 - 16-year follow-up of the Danish Acute Myocardial Infarction 2 trial - Primary percutaneous coronary intervention versus fibrinolysis in ST-elevation myocardial infarction

丹麦急性心肌梗死-2试验的16年随访结果:STEMI患者接受PCI与溶栓的比较


Hot Line Session 5


时间:Tue 03 Sep,11:00 - 12:30

地点:Paris - Main Auditorium


CLARIFY - In stable coronary disease, patients with angina and prior myocardial infarction have a poor prognosis despite adherence to guideline recommended therapies. Final 5-year results from the CLARIFY study

CLARIFY研究的5年最终结果:在稳定性冠状动脉疾病中,尽管依从指南推荐的治疗,既往心肌梗死且有心绞痛的患者预后仍然较差


SWEDEHEART - Secondary prevention medication after coronary artery bypass surgery and long-term mortality: A longitudinal population-based study from the SWEDEHEART registry

SWEDEHEART登记的纵向人群研究:冠状动脉搭桥术后患者使用药物进行二级预防对长期死亡率的影响


PURE - Contrasting patterns of cardiovascular disease, cancers and related mortality between high- versus low-middle income countries in 21 countries

在21个高收入和低中收入国家中,心血管疾病、癌症和相关死亡率的对比


ICD use in HF - Association between implantable cardioverter-defibrillator use for primary prevention and mortality: a prospective propensity-score matched study

植入式心律转复除颤器用于一级预防和死亡率的关联:一项前瞻性倾向评分匹配研究


FRANCE-TAVI - Balloon-expandable versus Self-expandable TAVR On ParaValvular Regurgitation And 2-year Mortality: a propensity-matched comparison from the France-TAVI Registry

球囊扩张与自扩张TAVR对瓣叶反流和2年死亡率的影响:对France-TAVI注册数据的倾向匹配比较


Hot Line Session 6


时间:Tue 03 Sep,16:40 - 17:52

地点:Paris - Main Auditorium


RAPID-TnT - A randomised trial of a 1-hour troponin T protocol in suspected acute coronary syndromes: the Rapid Assessment of Possible ACS In the emergency Department with high sensitivity Troponin T

一项随机试验,评估1小时高敏肌钙蛋白T方案对急诊科疑似急性冠脉综合征患者诊断的价值


ENTRUST-AF PCI - Edoxaban-based versus vitamin-K-antagonist-based anti-thrombotic regimen following successful coronary stenting in atrial fibrillation patients

在成功接受冠脉支架置入术后的房颤患者中,评估艾多沙班的方案与维生素K拮抗剂方案的抗栓治疗效果


POPular Genetics - Genotype-guided oral P2Y12-inhibition in patients with ST-segment elevation myocardial infarction undergoing primary PCI: a randomized, open-label, multicenter trial

一项随机、开放标签的多中心试验:在接受PCI治疗的STEMI患者中,评估基因型指导的口服P2Y12抑制剂治疗的作用


DAPA - Long-term outcome of the Defibrillator After Primary Angioplasty Trial - Implantable Defibrillator Early After Primary Percutaneous Intervention for ST-Elevation Myocardial infarction

在STEMI患者中,直接血管成形术(PPCI)后早期置入除颤器的长期结果评价


中欧联袂,开设2个联合专场


中华医学会心血管病学分会和长城国际心脏病学大会分别与ESC设立了联合专场。


9月2日16:40 - 17:50,ESC/CSC专场将就急性冠状动脉综合征患者的抗栓治疗展开讨论,介绍中国和欧洲在抗栓治疗领域的当前认识和临床研究。


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9月3日14:30 - 15:40,ESC/GWICC联合专场将就高风险ASCVD患者的血脂管理进行探讨,内容包括风险管理、患者的识别、PCSK9抑制剂的使用等,涉及多种危险因素和多种管理策略。


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ESC2019涉及400多个心血管领域热点话题,设置500余场专家讨论会,包括4500多篇研究摘要,来自150个国家的3.2万名心血管领域的专家学者将共聚巴黎,推动心血管学科的进步。


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专题>>> 2019年欧洲心脏病学会年会(ESC 2019)

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