在2017ESC年会上，浙江省人民医院钱琳艳教授带来了一项Rapid Fire Abstract口头报告，探讨了非高
医脉通：请您介绍一下这项研究及其临床意义？
钱琳艳教授：众所周知，脂肪肝与
最后的统计结果显示，血压在正常范围的患者，其
医脉通：当脂肪肝患者发生高血压后，其血压应该控制在什么水平？
钱琳艳教授：对于这个问题，我认为需要更长期的数据来解答。可能是5年或10年随访之后，我们才能知道干预或顺其自然的患者会怎样，这项研究对我们的临床工作还是有帮助的。
对于血压处于正常高值的脂肪肝患者，其血压再低一些会不会更好？这是个很复杂、很困难的问题。目前的降压指南对不同年龄、不同疾病状态的推荐有很多，但没有明确指出脂肪肝合并高血压患者必须怎样做。所以，对于这个问题，的确需要通过大样本数据才能得出结论。
研究摘要：Association of blood pressure level with nonalcoholic fatty liver disease in non-hypertensive population: normal is not the new normal
Background and aim: Some literatures have reported the relationship between NAFLD and hypertension, but there is no article describes the characteristic of NAFLD in non-hypertensive individuals. This study aimed to determine the strength of the association between NAFLD with normal BP in non-hypertensive individuals.
Method: A cross-sectional study was conducted among patients who came to the sixth Affiliated Hospital Medical University from October 2007 to December 2011.
Results: Of the 24200 enrolled subjects, 5305 filled the diagnostic criteria for NAFLD (21.9%; 4803 males and 502 females). Non-hypertension was identified in 17403 (71.9%; 8179 males and 9224 females). The PR% of NAFLD for the SBP in quartile 1, quartile 2, quartile 3, and quartile 4 was 10.83, 12.55, 20.38, and 19.97. SBP, DBP, sex, age, ALB, GPT, GOT, FPG, UA, TG, HDL-C and LDL-C are closely associated with the risk for NAFLD. SBP (OR: 1.092, 95% CI: 1.030–1.158; P<0.05) and DBP (OR: 1.157, 95% CI: 1.094–1.223; P<0.05) were found to be independent risk factors for NAFLD.
Conclusions: BP is significantly associated with NAFLD in non-hypertensive individuals; SBP and DBP are found to be independent risk factors for NAFLD.
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