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一年一度的欧洲肿瘤内科学会胃肠肿瘤年会(ESMO GI)将于2026年7月1日-4日在德国慕尼黑召开。日前,大会官网披露了入选研究摘要标题,医脉通特将入选口头报告(Proffered Paper Session及Rapid Oral Session)的标题整理如下,抢先带您一览重磅前沿研究内容!
Proffered Paper Session
摘要号:LBA1
英文标题:Second-line adagrasib plus cetuximab vs chemotherapy in patients with KRASG12C-mutated metastatic colorectal cancer: results from the KRYSTAL-10 trial
中文标题:KRYSTAL-10研究结果:adagrasib联合西妥昔单抗对比化疗二线治疗KRAS G12C突变转移性
讲者:Josep Tabernero | 西班牙
摘要号:LBA2
英文标题:Tumour response analyses by RECIST v1.1 and mRECIST in the Phase 3 EMERALD-3 study of tremelimumab plus durvalumab with or without lenvatinib plus transarterial chemoembolisation (TACE) in embolisation-eligible hepatocellular carcinoma (eeHCC)
中文标题:EMERALD-3 III期研究中,基于RECIST v1.1和mRECIST标准的肿瘤缓解分析:曲麦利尤单抗联合度伐利尤单抗±仑伐替尼联合经动脉化疗栓塞(TACE)治疗栓塞适用型
讲者:Joseph P. Erinjeri | 美国
摘要号:1O
英文标题:ATOMIC (A021502/AIO-KRK-0317): Does duration of adjuvant chemotherapy (chemo) or immunotherapy matter?
中文标题:ATOMIC研究(A021502/AIO-KRK-0317):辅助化疗或免疫治疗的持续时间是否重要?
讲者:Anke Reinacher-Schick | 德国
摘要号:8O
英文标题:ctDNA status and adjuvant chemotherapy after resection of colorectal liver metastases: an overall survival analysis of the GALAXY study
中文标题: 循环肿瘤DNA(ctDNA)状态与结直肠肝转移灶切除术后辅助化疗:GALAXY研究的总生存期分析
讲者:Kozo Kataoka | 日本
摘要号:183O
英文标题:Overall survival (OS) in EMERALD-1: a Phase 3 study of durvalumab (D) + bevacizumab (B) and transarterial chemoembolisation (TACE) in participants (pts) with unresectable embolisation-eligible hepatocellular carcinoma (eeHCC)
中文标题:EMERALD-1 III期研究的总生存期(OS)结果:度伐利尤单抗联合贝伐珠单抗及经动脉化疗栓塞术(TACE)治疗不可切除栓塞适用型肝细胞癌(eeHCC)
讲者:Bruno Sangro | 西班牙
摘要号:340O
英文标题:Safety and efficacy of zoldonrasib (RMC-9805) plus chemotherapy in patients (Pts) with 1L RAS G12D metastatic pancreatic adenocarcinoma (mPDAC)
中文标题:Zoldonrasib(RMC-9805)联合化疗一线治疗RAS G12D转移性
讲者:Brian M. Wolpin | 美国
摘要号:341O
英文标题:Safety and efficacy of zoldonrasib (RMC-9805) plus daraxonrasib (RMC-6236) in patients with 2L+ KRAS G12D metastatic pancreatic adenocarcinoma (mPDAC)
中文标题:Zoldonrasib(RMC-9805)联合daraxonrasib(RMC-6236)治疗二线及以上KRAS G12D转移性胰腺癌(mPDAC)患者的安全性和疗效
讲者:Nilofer S. Azad | 美国
摘要号:342O
英文标题:Zolbetuximab plus gemcitabine and nab-paclitaxel (GN) in patients (pts) with claudin 18 isoform 2 (CLDN18.2)+ metastatic pancreatic adenocarcinoma (mPAC): Phase II GLEAM study
中文标题:
讲者:Wungki Park | 美国
摘要号:493O
英文标题:STAR-221: A phase 3 study of first-line (1L) domvanalimab (D), zimberelimab (Z), and chemotherapy (chemo) vs nivolumab (N) + chemo in advanced HER2-negative gastric, gastroesophageal junction, or esophageal adenocarcinoma (GC/GEJC/EAC)
中文标题:STAR-221:domvanalimab+zimberelimab+化疗对比纳武利尤单抗+化疗一线治疗HER2阴性晚期
讲者:Sun Young Rha | 韩国
摘要号:494O
英文标题:Health-related quality of life (HRQoL) with zanidatamab (zani) + chemotherapy (CT) ± tislelizumab (TIS) for first-line (1L) HER2-positive (HER2+) advanced/metastatic gastroesophageal adenocarcinoma (mGEA): Results from HERIZON-GEA-01
中文标题:泽尼达妥单抗联合化疗±替雷利珠单抗一线治疗HER2阳性晚期/转移性胃食管腺癌(mGEA)的健康相关生活质量(HRQoL):HERIZON-GEA-01研究结果
讲者:Kohei Shitara | 日本
Rapid oral session
摘要号:LBA3
英文标题:Node-sparing Modified Short-Course Radiotherapy Combined with CAPOX and Tislelizumab Versus Conventional Short-Course Preoperative Chemoradiotherapy for pMMR or MSS Locally Advanced Rectal Cancer: A Multicenter, Randomized, Open-Label, Phase 3 Trial
中文标题:淋巴结豁免的改良短程放疗联合CAPOX方案及替雷利珠单抗对比短程术前放化疗治疗pMMR/MSS局部进展期直肠癌:一项多中心、随机、开放标签III期研究
讲者:宋章法 | 浙江大学医学院附属邵逸夫医院
摘要号:2RO
英文标题:Cetuximab in the continuum of care of molecularly selected metastatic colorectal cancer: The CAPRI-2 GOIM trial
中文标题:西妥昔单抗在分子筛选的转移性结直肠癌全程管理中的应用:CAPRI-2 GOIM研究
讲者:Giulia Martini | 意大利
摘要号:3RO
英文标题:Treatment strategy and immune-related toxicity shape response to neoadjuvant immunotherapy in dMMR/MSI-H colorectal cancer: Results from the AGEO-NEO-MSI study
中文标题:治疗策略与免疫相关毒性对dMMR/MSI-H结直肠癌新辅助免疫治疗应答的影响:AGEO-NEO-MSI研究结果
讲者:Annalice Gandini | 法国
摘要号:4RO
英文标题:Chemotherapy (CT) plus anti-EGFR retreatment versus CT switch plus anti-VEGF/R after progression in pMMR/MSS, RAS/BRAF wild-type metastatic colorectal cancer (mCRC): Individual patient data analysis of 5 randomized trials (RCTs)
中文标题:pMMR/MSS、RAS/BRAF野生型转移性结直肠癌进展后化疗联合抗EGFR再挑战对比换用化疗联合抗VEGF/R:5项随机对照试验的个体患者数据分析
讲者:Vittorio Studiale | 意大利
摘要号:5RO
英文标题:LAVA-CRLM: Randomised phase II trial of microwave ablation versus stereotactic body radiotherapy for oligometastatic colorectal liver metastases
中文标题:LAVA-CRLM:微波消融对比立体定向
讲者:Signe L. Risumlund | 丹麦
摘要号:184RO
英文标题:Real-world data from PROACTIF: Overall survival of hepatocellular carcinoma patients with large tumors or portal vein thrombosis treated with selective internal radioembolization therapy with yttrium-90
中文标题:PROACTIF真实世界数据:钇-90选择性体内放射栓塞治疗伴大肿瘤或门静脉癌栓形成的肝细胞癌患者的总生存期
讲者:Boris Guiu | 法国
摘要号:295RO
英文标题:Immunotherapy based total neoadjuvant therapy with or without short-course radiotherapy for locally advanced rectal cancer: Updated results of TORCH-iTNT
中文标题:免疫治疗为基础的全程新辅助治疗联合或不联合短程放疗用于局部晚期直肠癌:TORCH-iTNT更新结果
讲者:王雅琪 | 复旦大学附属肿瘤医院
Rapid oral session on innovation
摘要号:LBA4
英文标题:TRIPP-FFX: Results of an open-label, multi-centre, randomized study of TaRgeted Intratumoural Placement of Phosphorous-32 microparticles in addition to FOLFIRINOX versus FOLFIRINOX alone in patients with unresectable locally advanced pancreatic cancer (uLAPC)
中文标题:TRIPP-FFX研究:磷-32微粒子瘤内靶向植入联合FOLFIRINOX对比单纯FOLFIRINOX治疗不可切除局部晚期胰腺癌(uLAPC)的开放标签、多中心、随机研究结果
讲者:Michele Milella | 意大利
摘要号:6RO
英文标题:Calderasib (MK-1084) for KRAS G12C-mutated (mut) advanced colorectal cancer (CRC): Results from KANDLELIT-001
中文标题:Calderasib(MK-1084)治疗KRAS G12C突变晚期结直肠癌:KANDLELIT-001研究结果
讲者:Rafal Dziadziuszko | 波兰
摘要号:7RO
英文标题:Molecular correlates of enhanced outcome with first-line (1L) encorafenib + cetuximab (EC) ± mFOLFOX6 in BRAF V600E-mutant metastatic colorectal cancer (mCRC) from the BREAKWATER study
中文标题:BREAKWATER研究中一线恩考芬尼联合西妥昔单抗(EC)±mFOLFOX6在BRAF V600E突变转移性结直肠癌(mCRC)中增强疗效的分子相关因素分析
讲者:Scott Kopetz | 美国
摘要号:343RO
英文标题:Fanregratinib in fibroblast growth factor receptor 2 (FGFR2)-fusions/rearrangements intrahepatic cholangiocarcinoma (ICC): Pivotal part of a phase II trial
中文标题:Fanregratinib治疗FGFR2融合/重排肝内胆管癌(ICC):II期临床试验关键队列
讲者:徐建明 | 解放军总医院
摘要号:344RO
英文标题:A phase I study of futibatinib in combination with zimberelimab and chemotherapy in first-line unresectable advanced or metastatic biliary tract cancer
中文标题:Futibatinib联合zimberelimab和化疗一线治疗不可切除晚期或转移性胆道恶性肿瘤的I期研究
讲者:Kazuyoshi Ohkawa | 日本
摘要号:345RO
英文标题:Precemtabart tocentecan (Precem-TcT) in patients with metastatic pancreatic ductal adenocarcinoma (mPDAC): Results from the Phase Ib/II PROCEADE-PanTumor PDAC substudy
中文标题:Precemtabart tocentecan(Precem-TcT)治疗转移性胰腺导管腺癌(mPDAC)患者:Ib/II期PROCEADE-PanTumor胰腺癌亚组研究结果
讲者:Zev A. Wainberg | 美国
摘要号:495RO
英文标题:HERIZON-GEA-01: Exploratory analysis of response characteristics and PFS2 in advanced or metastatic gastroesophageal adenocarcinoma (mGEA)
中文标题:HERIZON-GEA-01:晚期或转移性胃食管腺癌(mGEA)缓解特征和PFS2的探索性分析
讲者:Filippo Pietrantonio | 意大利
摘要号:496RO
英文标题:Interchangeability of PD-L1 assays and scoring methods in gastroesophageal adenocarcinoma: The EORTC ASPIRE project
中文标题:胃食管腺癌中PD-L1检测方法和评分系统的可互换性:EORTC ASPIRE项目
讲者:Angelica Petrillo | 意大利
备注:排名不分先后,按照摘要号进行排序
如有遗漏或任何问题,请给我们留言~
来源:ESMO GI官网
撰写:Aurora
排版:Aurora
执行:Aurora